News from aidsmap
The European Commission has granted marketing authorisation for tenofovir alafenamide, to be sold under the brand name Vemlidy, for the treatment of chronic hepatitis B virus (HBV) infection, according to an announcement from Gilead Sciences.
The provision of regular low-value economic incentives can improve adherence to antiretroviral therapy (ART), according to research conducted in Uganda and published in the online edition of AIDS. People were eligible for prizes worth approximately $1.50 if they attended their clinic appointments or took at least 90% of the ART doses as evaluated using electronic monitoring.
Providing pre-exposure prophylaxis (PrEP) to people who need it entails at least nine key steps, which can be conceived of as a PrEP continuum of care, according to an article published online ahead of print by Amy Nunn and colleagues in AIDS. This continuum can help define benchmarks by which progress in implementing PrEP in different programmes can be compared.
People over the age of 50 now represent one third of all people living with HIV, but the social care, healthcare and welfare systems aren’t ready for this growing cohort, according to research published by the Terrence Higgins Trust. They describe the situation as a ‘social care timebomb’.
People living with HIV who take statins are less likely to experience cholesterol reductions and more likely to develop painful muscle damage as a side-effect if they have vitamin D deficiency, studies published this month in two journals show.
The vast majority of people taking antiretroviral therapy (ART) in the UK have an accurate knowledge of their current viral load (VL) level, investigators report in HIV Medicine. Overall, 96% of people who told researchers their viral load was undetectable had a clinic-recorded viral load below 50 copies/ml, with 99% having a viral load below 1000 copies/ml.
Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million to a Boston drug device manufacturer to develop an implantable mini-pump to deliver drugs for pre-exposure prophylaxis (PrEP) against HIV infection has focused attention on the future of PrEP. Is the future all about implants, or will it offer multiple options for people who want to use PrEP?
Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – in HIV-positive women, US investigators report in the online edition of AIDS. Researchers from the large Women’s Interagency HIV Study (WIHS) examined the impact of smoking on pregnancy loss in HIV-positive and HIV-negative women over a 20-year period. The effect of smoking on pregnancy loss differed dramatically by HIV status, increasing the absolute risk by 19% in HIV-positive women compared to 10% in HIV-positive women.
A risk score based on routine assessments carried out during antenatal care in resource-limited settings can accurately predict which pregnant and breastfeeding women have an especially high risk of infection with HIV and would therefore benefit from pre-exposure prophylaxis (PrEP), investigators report in the online edition of Clinical Infectious Diseases.
Editors’ picks from other sources
The worst form of drug-resistant tuberculosis isn’t just arising from inadequate treatment, it’s mostly being spread from person to person, according to a new study of hundreds of cases in South Africa.
from The Atlantic
A questionnaire from the president-elect’s transition team asked whether the extraordinarily successful PEPFAR had become a “massive, international entitlement program,” and whether it was worth the investment.
PrEP is largely failing to help those who need an HIV prevention game changer most desperately, namely black men who have sex with men, in particular those younger than 25.
The US Government could cure most Americans suffering from hepatitis C infections if it simply bought drug maker Gilead Sciences on the stock market rather than purchasing its products in the drug market.
Britain could soon see its first “fix room” for drug users – a safe space where addicts can take illegal narcotics under medical supervision. But who uses such places and how do they work?